Role of glutathione S-transferase P-1 (GSTP-1) gene polymorphism in COPD patients
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چکیده
منابع مشابه
Glutathione S-transferase M1 gene polymorphism in Thai nasopharyngeal carcinoma.
Nasopharyngeal carcinoma (NPC) is a serious health problem in Thailand. It is caused by the combined effects of Epstein-Barr virus (EBV), carcinogens and genetic susceptibility. The glutathione S-transferase M1 gene (GSTM1) encodes a phase II enzyme responsible for detoxifying carcinogenic electrophiles. Polymorphic null forms of the gene GSTM1 lack enzyme activity and have been associated with...
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* To whom correspondence should be addressed: T: +441382 383134 F: +441382 386419 E: [email protected] Running Title: human GSTP reporter mouse
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We have characterized a Drosophila glutathione S-transferase (RX:glutathione R-transferase, EC 2.5.1.18) cDNA encoding a protein of 209 amino acids. The cDNA was expressed in Escherichia coli harboring the expression plasmid construct pGTDml-KK. The active enzyme, designated as Drosophila glutathione S-transferase 1-1, had a specific activity toward 1-chloro-2,4-dinitrobenzene comparable to tha...
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ژورنال
عنوان ژورنال: Egyptian Journal of Chest Diseases and Tuberculosis
سال: 2016
ISSN: 0422-7638
DOI: 10.1016/j.ejcdt.2015.06.008